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mavorixafor will increase the degree or result of codeine by influencing hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a strong CYP2D6 inhibitor) is contraindicated with medication which can be extremely dependent on CYP2D6 for clearance.Sildenafil citrate is usually a type of drug identified as a PDE5 inhibitor, which just means